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By Sushmita Mitra

"Shedding gentle on elements of either desktop studying and bioinformatics, this article exhibits how the cutting edge instruments and methods of computing device studying aid extract wisdom from the deluge of knowledge produced by way of contemporary organic experiments."--Jacket.

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Introduction to machine learning and bioinformatics

"Shedding mild on features of either computer studying and bioinformatics, this article exhibits how the cutting edge instruments and methods of computing device studying aid extract wisdom from the deluge of data produced through cutting-edge organic experiments. "--Jacket.

Extra resources for Introduction to machine learning and bioinformatics

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Any of three codons, UAA, UAG and UGA indicate the end of the protein and that translation should stop. In eukaryotes, ribosomes bind to the start of the transcript and move along it until encountering the first AUG codon, where translation begins. Sometimes, the translating machinery will skip over the first or even second occurrence of AUG and begin at the next occurrence. This skipping is influenced by the adjacent nucleotides, and is another mechanism by which different variants of a protein are created from the same DNA coding region.

In order to do that, we must look for any kind of pattern or regularity that uncertainty may exhibit. And fortunately, it often does exhibit discernible patterns in real life. For example, if it is cloudy and raining right now at a certain latitude and longitude, exactly predicting the weather condition at that spot 24 hours from now may not be possible, but we can at least browse through the extensive weather records for the past hundred years and find out how the weather has changed (or not changed) in a 24-hour period at that particular location on rainy days during the same season.

How different these are from the long-term frequency-based probabilities will depend on how realistic our models are and/or how correct our logical reasoning is. For instance, if our random experiment is picking a ball without looking from a box containing 50 balls of identical size and 5 different colors red, black, white, purple and yellow (10 balls of each color), our logical reasoning will lead us to assign a probability of 15 to each of the outcomes {R, B, W, P, Y }. This will indeed coincide with the long-term frequency of each of the colors because the balls are otherwise identical.

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